Immune protection against reinfection with nonprimate hepacivirus

Hepatitis C virus (HCV) displays a restricted host species tropism and only humans and chimpanzees are susceptible to infection. A robust immunocompetent animal model is still lacking, hampering mechanistic analysis of virus pathogenesis, immune control, and prophylactic vaccine development. The clo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Pfaender, Stephanie, Walter, Stephanie, Grabski, Elena, Todt, Daniel, Bruening, Janina, Romero-Brey, Inés, Gather, Theresa, Brown, Richard J. P., Hahn, Kerstin, Puff, Christina, Pfankuche, Vanessa M., Hansmann, Florian, Postel, Alexander, Becher, Paul, Thiel, Volker, Kalinke, Ulrich, Wagner, Bettina, Bartenschlager, Ralf, Baumgärtner, Wolfgang, Feige, Karsten, Pietschmann, Thomas, Cavalleri, Jessika M. V., Steinmann, Eike
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373355/
https://ncbi.nlm.nih.gov/pubmed/28275093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619380114
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