Immune protection against reinfection with nonprimate hepacivirus

Hepatitis C virus (HCV) displays a restricted host species tropism and only humans and chimpanzees are susceptible to infection. A robust immunocompetent animal model is still lacking, hampering mechanistic analysis of virus pathogenesis, immune control, and prophylactic vaccine development. The clo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Pfaender, Stephanie, Walter, Stephanie, Grabski, Elena, Todt, Daniel, Bruening, Janina, Romero-Brey, Inés, Gather, Theresa, Brown, Richard J. P., Hahn, Kerstin, Puff, Christina, Pfankuche, Vanessa M., Hansmann, Florian, Postel, Alexander, Becher, Paul, Thiel, Volker, Kalinke, Ulrich, Wagner, Bettina, Bartenschlager, Ralf, Baumgärtner, Wolfgang, Feige, Karsten, Pietschmann, Thomas, Cavalleri, Jessika M. V., Steinmann, Eike
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2017
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373355/
https://ncbi.nlm.nih.gov/pubmed/28275093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619380114
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