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Genetic Diversity Underlying the Envelope Glycoproteins of Hepatitis C Virus: Structural and Functional Consequences and the Implications for Vaccine Design

In the 26 years since the discovery of Hepatitis C virus (HCV) a major global research effort has illuminated many aspects of the viral life cycle, facilitating the development of targeted antivirals. Recently, effective direct-acting antiviral (DAA) regimens with >90% cure rates have become avai...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Tarr, Alexander W., Khera, Tanvi, Hueging, Kathrin, Sheldon, Julie, Steinmann, Eike, Pietschmann, Thomas, Brown, Richard J. P.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517138/
https://ncbi.nlm.nih.gov/pubmed/26193307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7072809
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