Intercompartmental Recombination of HIV-1 Contributes to env Intrahost Diversity and Modulates Viral Tropism and Sensitivity to Entry Inhibitors

HIV-1 circulates within an infected host as a genetically heterogeneous viral population. Viral intrahost diversity is shaped by substitutional evolution and recombination. Although many studies have speculated that recombination could have a significant impact on viral phenotype, this has never bee...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Brown, Richard J. P., Peters, Paul J., Caron, Catherine, Gonzalez-Perez, Maria Paz, Stones, Leanne, Ankghuambom, Chiambah, Pondei, Kemebradikumo, McClure, C. Patrick, Alemnji, George, Taylor, Stephen, Sharp, Paul M., Clapham, Paul R., Ball, Jonathan K.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2011
الموضوعات:
Genetic Diversity and Evolution
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126287/
https://ncbi.nlm.nih.gov/pubmed/21471230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00131-11
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