Correlative Biomarker Analysis of Intrinsic Subtypes and Efficacy Across the MONALEESA Phase III Studies

по Prat, Aleix, Chaudhury, Anwesha, Solovieff, Nadia, Paré, Laia, Martinez, Débora, Chic, Nuria, Martínez-Sáez, Olga, Brasó-Maristany, Fara, Lteif, Agnes, Taran, Tetiana, Babbar, Naveen, Su, Fei
Опубликовано в: J Clin Oncol (2021)

Frequency and spectrum of PIK3CA somatic mutations in breast cancer

по Martínez-Sáez, Olga, Chic, Nuria, Pascual, Tomás, Adamo, Barbara, Vidal, Maria, González-Farré, Blanca, Sanfeliu, Esther, Schettini, Francesco, Conte, Benedetta, Brasó-Maristany, Fara, Rodríguez, Adela, Martínez, Débora, Galván, Patricia, Rodríguez, Ana Belén, Martinez, Antonio, Muñoz, Montserrat, Prat, Aleix
Опубликовано в: Breast Cancer Res (2020)

Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer

по Patel, Nirmesh, Weekes, Daniel, Drosopoulos, Konstantinos, Gazinska, Patrycja, Noel, Elodie, Rashid, Mamun, Mirza, Hasan, Quist, Jelmar, Brasó-Maristany, Fara, Mathew, Sumi, Ferro, Riccardo, Pereira, Ana Mendes, Prince, Cynthia, Noor, Farzana, Francesch-Domenech, Erika, Marlow, Rebecca, de Rinaldis, Emanuele, Grigoriadis, Anita, Linardopoulos, Spiros, Marra, Pierfrancesco, Tutt, Andrew N. J.
Опубликовано в: Nat Commun (2018)

Oestrogen receptor activity in hormone-dependent breast cancer during chemotherapy

по Chic, Nuria, Schettini, Francesco, Brasó-Maristany, Fara, Sanfeliu, Esther, Adamo, Barbara, Vidal, Maria, Martínez, Débora, Galván, Patricia, González-Farré, Blanca, Cortés, Javier, Gavilá, Joaquín, Saura, Cristina, Oliveira, Mafalda, Pernas, Sònia, Martínez-Sáez, Olga, Soberino, Jesús, Ciruelos, Eva, Carey, Lisa A., Muñoz, Montserrat, Perou, Charles M., Pascual, Tomás, Bellet, Meritxell, Prat, Aleix
Опубликовано в: EBioMedicine (2021)

Circulating tumor DNA dynamics in advanced breast cancer treated with CDK4/6 inhibition and endocrine therapy

по Martínez-Sáez, Olga, Pascual, Tomás, Brasó-Maristany, Fara, Chic, Nuria, González-Farré, Blanca, Sanfeliu, Esther, Rodríguez, Adela, Martínez, Débora, Galván, Patricia, Rodríguez, Anna Belén, Schettini, Francesco, Conte, Benedetta, Vidal, Maria, Adamo, Barbara, Martínez, Antoni, Muñoz, Montserrat, Moreno, Reinaldo, Villagrasa, Patricia, Salvador, Fernando, Ciruelos, Eva M., Faull, Iris, Odegaard, Justin I., Prat, Aleix
Опубликовано в: NPJ Breast Cancer (2021)

Phenotypic changes of HER2-positive breast cancer during and after dual HER2 blockade

по Brasó-Maristany, Fara, Griguolo, Gaia, Pascual, Tomás, Paré, Laia, Nuciforo, Paolo, Llombart-Cussac, Antonio, Bermejo, Begoña, Oliveira, Mafalda, Morales, Serafín, Martínez, Noelia, Vidal, Maria, Adamo, Barbara, Martínez, Olga, Pernas, Sonia, López, Rafael, Muñoz, Montserrat, Chic, Núria, Galván, Patricia, Garau, Isabel, Manso, Luis, Alarcón, Jesús, Martínez, Eduardo, Gregorio, Sara, Gomis, Roger R., Villagrasa, Patricia, Cortés, Javier, Ciruelos, Eva, Prat, Aleix
Опубликовано в: Nat Commun (2020)

ERBB2 mRNA Expression and Response to Ado-Trastuzumab Emtansine (T-DM1) in HER2-Positive Breast Cancer

по Griguolo, Gaia, Brasó-Maristany, Fara, González-Farré, Blanca, Pascual, Tomás, Chic, Núria, Saurí, Tamara, Kates, Ronald, Gluz, Oleg, Martínez, Débora, Paré, Laia, Tsvetkova, Vassilena, Pesantez, David, Vidal, Maria, Adamo, Barbara, Muñoz, Montserrat, Galván, Patricia, Barberá, Laura, Cuatrecasas, Miriam, Christgen, Mathias, Kreipe, Hans, Monge-Escartín, Inés, Villagrasa, Patricia, Soy, Dolors, Giarratano, Tommaso, Dieci, Maria Vittoria, Conte, Pierfranco, Harbeck, Nadia, Guarneri, Valentina, Prat, Aleix
Опубликовано в: Cancers (Basel) (2020)

Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer

по Schettini, Francesco, Chic, Nuria, Brasó-Maristany, Fara, Paré, Laia, Pascual, Tomás, Conte, Benedetta, Martínez-Sáez, Olga, Adamo, Barbara, Vidal, Maria, Barnadas, Esther, Fernández-Martinez, Aranzazu, González-Farre, Blanca, Sanfeliu, Esther, Cejalvo, Juan Miguel, Perrone, Giuseppe, Sabarese, Giovanna, Zalfa, Francesca, Peg, Vicente, Fasani, Roberta, Villagrasa, Patricia, Gavilá, Joaquín, Barrios, Carlos H., Lluch, Ana, Martín, Miguel, Locci, Mariavittoria, De Placido, Sabino, Prat, Aleix
Опубликовано в: NPJ Breast Cancer (2021)

PIM1 kinase regulates cell death, tumor growth and chemotherapy response revealing a novel target in triple-negative breast cancer

по Brasó-Maristany, Fara, Filosto, Simone, Catchpole, Steven, Marlow, Rebecca, Quist, Jelmar, Francesch-Domenech, Erika, Plumb, Darren A., Zakka, Leila, Gazinska, Patrycja, Liccardi, Gianmaria, Meier, Pascal, Gris-Oliver, Albert, Cheang, Maggie Chon U, Perdrix-Rosell, Anna, Shafat, Manar, Noël, Elodie, Patel, Nirmesh, McEachern, Kristen, Scaltriti, Maurizio, Castel, Pau, Noor, Farzana, Buus, Richard, Mathew, Sumi, Watkins, Johnathan, Serra, Violeta, Marra, Pierfrancesco, Grigoriadis, Anita, Tutt, Andrew N.
Опубликовано в: Nat Med (2016)

HER2-enriched subtype and pathological complete response in HER2-positive breast cancer: a systematic review and meta-analysis

по Schettini, Francesco, Pascual, Tomas, Conte, Benedetta, Chic, Nuria, Brasó-Maristany, Fara, Galván, Patricia, Martínez, Olga, Adamo, Barbara, Vidal, Maria, Muñoz, Montserrat, Fernández-Martinez, Aranzazu, Rognoni, Carla, Griguolo, Gaia, Guarneri, Valentina, Conte, Pier Franco, Locci, Mariavittoria, Brase, Jan C., Gonzalez-Farre, Blanca, Villagrasa, Patricia, De Placido, Sabino, Schiff, Rachel, Veeraraghavan, Jamunarani, Rimawi, Mothaffar F., Osborne, C. Kent, Pernas, Sonia, Perou, Charles M., Carey, Lisa A., Prat, Aleix
Опубликовано в: Cancer Treat Rev (2020)

FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease

по Garcia-Recio, Susana, Thennavan, Aatish, East, Michael P., Parker, Joel S., Cejalvo, Juan M., Garay, Joseph P., Hollern, Daniel P., He, Xiaping, Mott, Kevin R., Galván, Patricia, Fan, Cheng, Selitsky, Sara R., Coffey, Alisha R., Marron, David, Brasó-Maristany, Fara, Burgués, Octavio, Albanell, Joan, Rojo, Federico, Lluch, Ana, de Dueñas, Eduardo Martinez, Rosen, Jeffery M., Johnson, Gary L., Carey, Lisa A., Prat, Aleix, Perou, Charles M.
Опубликовано в: J Clin Invest (2020)

Genetic alterations in the PI3K/AKT pathway and baseline AKT activity define AKT inhibitor sensitivity in breast cancer patient-derived xenografts

по Gris-Oliver, Albert, Palafox, Marta, Monserrat, Laia, Brasó-Maristany, Fara, Òdena, Andreu, Sánchez-Guixé, Mònica, Ibrahim, Yasir H., Villacampa, Guillermo, Grueso, Judit, Parés, Mireia, Guzmán, Marta, Rodríguez, Olga, Bruna, Alejandra, Hirst, Caroline S., Barnicle, Alan, de Bruin, Elza, Reddy, Avinash, Schiavon, Gaia, Arribas, Joaquín, Mills, Gordon B., Caldas, Carlos, Dienstmann, Rodrigo, Prat, Aleix, Nuciforo, Paolo, Razavi, Pedram, Scaltriti, Maurizio, Turner, Nicholas C., Saura, Cristina, Davies, Barry R., Oliveira, Mafalda, Serra, Violeta
Опубликовано в: Clin Cancer Res (2020)

HER2-Enriched Subtype and ERBB2 Expression in HER2-Positive Breast Cancer Treated with Dual HER2 Blockade

по Prat, Aleix, Pascual, Tomás, De Angelis, Carmine, Gutierrez, Carolina, Llombart-Cussac, Antonio, Wang, Tao, Cortés, Javier, Rexer, Brent, Paré, Laia, Forero, Andres, Wolff, Antonio C, Morales, Serafín, Adamo, Barbara, Brasó-Maristany, Fara, Vidal, Maria, Veeraraghavan, Jamunarani, Krop, Ian, Galván, Patricia, Pavlick, Anne C, Bermejo, Begoña, Izquierdo, Miguel, Rodrik-Outmezguine, Vanessa, Reis-Filho, Jorge S, Hilsenbeck, Susan G, Oliveira, Mafalda, Dieci, Maria Vittoria, Griguolo, Gaia, Fasani, Roberta, Nuciforo, Paolo, Parker, Joel S, Conte, PierFranco, Schiff, Rachel, Guarneri, Valentina, Osborne, C Kent, Rimawi, Mothaffar F
Опубликовано в: J Natl Cancer Inst (2019)

Development of a multi-parameter prognostic score to guide systemic therapy in early-stage HER2-positive breast cancer: a retrospective study with an external evaluation

по Prat, Aleix, Guarneri, Valentina, Paré, Laia, Griguolo, Gaia, Pascual, Tomás, Dieci, Maria Vittoria, Chic, Núria, González-Farré, Blanca, Frassoldati, Antonio, Sanfeliu, Esther, Cejalvo, Juan Miguel, Muñoz, Montserrat, Bisagni, Giancarlo, Brasó-Maristany, Fara, Urso, Loredana, Vidal, Maria, Brandes, Alba Ariela, Adamo, Barbara, Musolino, Antonino, Miglietta, Federica, Conte, Benedetta, Oliveira, Mafalda, Saura, Cristina, Pernas, Sònia, Alarcón, Jesús, Llombart-Cussac, Antonio, Cortés, Javier, Manso, Luis, López, Rafael, Ciruelos, Eva, Schettini, Francesco, Villagrasa, Patricia, Carey, Lisa A., Perou, Charles M., Piacentini, Federico, D’Amico, Roberto, Tagliafico, Enrico, Parker, Joel. S., Conte, Pierfranco
Опубликовано в: Lancet Oncol (2020)