Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

by Bakota, Lidia, Brandt, Roland
Published in Drugs (2016)

Divergent Pathways Mediate Spine Alterations and Cell Death Induced by Amyloid-β, Wild-Type Tau, and R406W Tau

by Tackenberg, Christian, Brandt, Roland
Published in J Neurosci (2009)

Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells

by Heinisch, Jürgen J., Brandt, Roland
Published in Microb Cell (2016)

Tau-Mediated Cytotoxicity in a Pseudohyperphosphorylation Model of Alzheimer's Disease

by Fath, Thomas, Eidenmüller, Jochen, Brandt, Roland
Published in J Neurosci (2002)

Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau

by Brandt, Roland, Trushina, Nataliya I., Bakota, Lidia
Published in Front Neurol (2020)

Real‐time three‐dimensional echocardiographic diagnosis of postmyocardial infarction ventricular septal defect and guidance of transcatheter closure

by Brandt, Roland R, Elsaesser, Albrecht, Hamm, Christian W
Published 2007

Tau Binds to the Distal Axon Early in Development of Polarity in a Microtubule- and Microfilament-Dependent Manner

by Kempf, Martina, Clement, Albrecht, Faissner, Andreas, Lee, Gloria, Brandt, Roland
Published in J Neurosci (1996)

Tau Aggregation and Progressive Neuronal Degeneration in the Absence of Changes in Spine Density and Morphology after Targeted Expression of Alzheimer's Disease-Relevant Tau Constr...

by Shahani, Neelam, Subramaniam, Srinivasa, Wolf, Tobias, Tackenberg, Christian, Brandt, Roland
Published in J Neurosci (2006)

The Evolution of Tau Phosphorylation and Interactions

by Trushina, Nataliya I., Bakota, Lidia, Mulkidjanian, Armen Y., Brandt, Roland
Published in Front Aging Neurosci (2019)

A Refined Reaction-Diffusion Model of Tau-Microtubule Dynamics and Its Application in FDAP Analysis

by Igaev, Maxim, Janning, Dennis, Sündermann, Frederik, Niewidok, Benedikt, Brandt, Roland, Junge, Wolfgang
Published in Biophys J (2014)

Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau’s interaction with microtubules in axon-like processes

by Niewidok, Benedikt, Igaev, Maxim, Sündermann, Frederik, Janning, Dennis, Bakota, Lidia, Brandt, Roland
Published in Mol Biol Cell (2016)

Evaluation Of Atrial Fibrillation Burden Before Catheter Ablation Predicts Outcome After Pulmonary Vein Isolation

by Berkowitsch, Alexander, Neumann, Thomas, Kuniss, Malte, Brandt, Roland, Zaltsberg, Sergej, Pitschner, Heinz F
Published 2009

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative process...

by Golovyashkina, Nataliya, Penazzi, Lorène, Ballatore, Carlo, Smith, Amos B., Bakota, Lidia, Brandt, Roland
Published in Mol Neurodegener (2015)

Insulin-Like Growth Factor 1 Inhibits Extracellular Signal-Regulated Kinase to Promote Neuronal Survival via the Phosphatidylinositol 3-Kinase/Protein Kinase A/c-Raf Pathway

by Subramaniam, Srinivasa, Shahani, Neelam, Strelau, Jens, Laliberté, Christine, Brandt, Roland, Kaplan, David, Unsicker, Klaus
Published in J Neurosci (2005)

Process Outgrowth of Oligodendrocytes Is Promoted by Interaction of Fyn Kinase with the Cytoskeletal Protein Tau

by Klein, Corinna, Krämer, Eva-Maria, Cardine, Anne-Marie, Schraven, Burkhardt, Brandt, Roland, Trotter, Jacqueline
Published in J Neurosci (2002)

Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease

by Deng, Yanqiu, Li, Bin, Liu, Fei, Iqbal, Khalid, Grundke-Iqbal, Inge, Brandt, Roland, Gong, Cheng-Xin
Published 2007

RNA Protein Granules Modulate tau Isoform Expression and Induce Neuronal Sprouting

by Moschner, Katharina, Sündermann, Frederik, Meyer, Heiko, da Graca, Abel Pereira, Appel, Neele, Paululat, Achim, Bakota, Lidia, Brandt, Roland
Published 2014

Pseudohyperphosphorylation of tau is sufficient to induce aberrant sprouting and activation of ERK1/2 in transgenic mice

by Monyer Hannah, von Engelhardt Jacob, Götz Jürgen, Schultz Christian, Fath Thomas, Kosfeld Anne, Selle Karolin, Hundelt Monika, Brandt Roland
Published 2007-03-01

The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner

by Gauthier-Kemper, Anne, Weissmann, Carina, Golovyashkina, Nataliya, Sebö-Lemke, Zsofia, Drewes, Gerard, Gerke, Volker, Heinisch, Jürgen J., Brandt, Roland
Published 2011

Early Effects of Aβ Oligomers on Dendritic Spine Dynamics and Arborization in Hippocampal Neurons

by Ortiz-Sanz, Carolina, Gaminde-Blasco, Adhara, Valero, Jorge, Bakota, Lidia, Brandt, Roland, Zugaza, José L., Matute, Carlos, Alberdi, Elena
Published in Front Synaptic Neurosci (2020)