Tau Biology and Tau-Directed Therapies for Alzheimer’s Disease

per Bakota, Lidia, Brandt, Roland
Publicat a Drugs (2016)

Divergent Pathways Mediate Spine Alterations and Cell Death Induced by Amyloid-β, Wild-Type Tau, and R406W Tau

per Tackenberg, Christian, Brandt, Roland
Publicat a J Neurosci (2009)

Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells

per Heinisch, Jürgen J., Brandt, Roland
Publicat a Microb Cell (2016)

Tau-Mediated Cytotoxicity in a Pseudohyperphosphorylation Model of Alzheimer's Disease

per Fath, Thomas, Eidenmüller, Jochen, Brandt, Roland
Publicat a J Neurosci (2002)

Much More Than a Cytoskeletal Protein: Physiological and Pathological Functions of the Non-microtubule Binding Region of Tau

per Brandt, Roland, Trushina, Nataliya I., Bakota, Lidia
Publicat a Front Neurol (2020)

Real‐time three‐dimensional echocardiographic diagnosis of postmyocardial infarction ventricular septal defect and guidance of transcatheter closure

per Brandt, Roland R, Elsaesser, Albrecht, Hamm, Christian W
Publicat 2007

Tau Binds to the Distal Axon Early in Development of Polarity in a Microtubule- and Microfilament-Dependent Manner

per Kempf, Martina, Clement, Albrecht, Faissner, Andreas, Lee, Gloria, Brandt, Roland
Publicat a J Neurosci (1996)

Tau Aggregation and Progressive Neuronal Degeneration in the Absence of Changes in Spine Density and Morphology after Targeted Expression of Alzheimer's Disease-Relevant Tau Constr...

per Shahani, Neelam, Subramaniam, Srinivasa, Wolf, Tobias, Tackenberg, Christian, Brandt, Roland
Publicat a J Neurosci (2006)

The Evolution of Tau Phosphorylation and Interactions

per Trushina, Nataliya I., Bakota, Lidia, Mulkidjanian, Armen Y., Brandt, Roland
Publicat a Front Aging Neurosci (2019)

A Refined Reaction-Diffusion Model of Tau-Microtubule Dynamics and Its Application in FDAP Analysis

per Igaev, Maxim, Janning, Dennis, Sündermann, Frederik, Niewidok, Benedikt, Brandt, Roland, Junge, Wolfgang
Publicat a Biophys J (2014)

Presence of a carboxy-terminal pseudorepeat and disease-like pseudohyperphosphorylation critically influence tau’s interaction with microtubules in axon-like processes

per Niewidok, Benedikt, Igaev, Maxim, Sündermann, Frederik, Janning, Dennis, Bakota, Lidia, Brandt, Roland
Publicat a Mol Biol Cell (2016)

Evaluation Of Atrial Fibrillation Burden Before Catheter Ablation Predicts Outcome After Pulmonary Vein Isolation

per Berkowitsch, Alexander, Neumann, Thomas, Kuniss, Malte, Brandt, Roland, Zaltsberg, Sergej, Pitschner, Heinz F
Publicat 2009

Region-specific dendritic simplification induced by Aβ, mediated by tau via dysregulation of microtubule dynamics: a mechanistic distinct event from other neurodegenerative process...

per Golovyashkina, Nataliya, Penazzi, Lorène, Ballatore, Carlo, Smith, Amos B., Bakota, Lidia, Brandt, Roland
Publicat a Mol Neurodegener (2015)

Insulin-Like Growth Factor 1 Inhibits Extracellular Signal-Regulated Kinase to Promote Neuronal Survival via the Phosphatidylinositol 3-Kinase/Protein Kinase A/c-Raf Pathway

per Subramaniam, Srinivasa, Shahani, Neelam, Strelau, Jens, Laliberté, Christine, Brandt, Roland, Kaplan, David, Unsicker, Klaus
Publicat a J Neurosci (2005)

Process Outgrowth of Oligodendrocytes Is Promoted by Interaction of Fyn Kinase with the Cytoskeletal Protein Tau

per Klein, Corinna, Krämer, Eva-Maria, Cardine, Anne-Marie, Schraven, Burkhardt, Brandt, Roland, Trotter, Jacqueline
Publicat a J Neurosci (2002)

Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease

per Deng, Yanqiu, Li, Bin, Liu, Fei, Iqbal, Khalid, Grundke-Iqbal, Inge, Brandt, Roland, Gong, Cheng-Xin
Publicat 2007

RNA Protein Granules Modulate tau Isoform Expression and Induce Neuronal Sprouting

per Moschner, Katharina, Sündermann, Frederik, Meyer, Heiko, da Graca, Abel Pereira, Appel, Neele, Paululat, Achim, Bakota, Lidia, Brandt, Roland
Publicat 2014

Pseudohyperphosphorylation of tau is sufficient to induce aberrant sprouting and activation of ERK1/2 in transgenic mice

per Monyer Hannah, von Engelhardt Jacob, Götz Jürgen, Schultz Christian, Fath Thomas, Kosfeld Anne, Selle Karolin, Hundelt Monika, Brandt Roland
Publicat 2007-03-01

The frontotemporal dementia mutation R406W blocks tau’s interaction with the membrane in an annexin A2–dependent manner

per Gauthier-Kemper, Anne, Weissmann, Carina, Golovyashkina, Nataliya, Sebö-Lemke, Zsofia, Drewes, Gerard, Gerke, Volker, Heinisch, Jürgen J., Brandt, Roland
Publicat 2011

Early Effects of Aβ Oligomers on Dendritic Spine Dynamics and Arborization in Hippocampal Neurons

per Ortiz-Sanz, Carolina, Gaminde-Blasco, Adhara, Valero, Jorge, Bakota, Lidia, Brandt, Roland, Zugaza, José L., Matute, Carlos, Alberdi, Elena
Publicat a Front Synaptic Neurosci (2020)