Canine and Feline Models of Human Genetic Diseases and Their Contributions to Advancing Clinical Therapies


Por Gurda, Brittney L., Bradbury, Allison M., Vite, Charles H.
Publicado no Yale J Biol Med (2017)

A Review of Gene Therapy in Canine and Feline Models of Lysosomal Storage Disorders

Por Bradbury, Allison M., Gurda, Brittney L., Casal, Margret L., Ponder, Katherine P., Vite, Charles H., Haskins, Mark E.
Publicado no Hum Gene Ther Clin Dev (2015)

Clinical, electrophysiological, and biochemical markers of peripheral and central nervous system disease in canine globoid cell leukodystrophy (Krabbe disease)

Por Bradbury, Allison M., Bagel, Jessica H., Jiang, Xuntian, Swain, Gary P., Prociuk, Maria L., Fitzgerald, Caitlin A., ODonnell, Patricia A., Braund, Kyle G., Ory, Daniel S., Vite, Charles H.
Publicado no J Neurosci Res (2016)

High resolution MRI anatomy of the cat brain at 3 Tesla

Por Gray-Edwards, Heather L., Salibi, Nouha, Josephson, Eleanor M., Hudson, Judith A., Cox, Nancy R., Randle, Ashley N., McCurdy, Victoria J., Bradbury, Allison M., Wilson, Diane U., Beyers, Ronald J., Denney, Thomas S., Martin, Douglas R.
Publicado em 2014

AAV-Mediated Gene Delivery in a Feline Model of Sandhoff Disease Corrects Lysosomal Storage in the Central Nervous System

Por Rockwell, Hannah E., McCurdy, Victoria J., Eaton, Samuel C., Wilson, Diane U., Johnson, Aime K., Randle, Ashley N., Bradbury, Allison M., Gray-Edwards, Heather L., Baker, Henry J., Hudson, Judith A., Cox, Nancy R., Sena-Esteves, Miguel, Seyfried, Thomas N., Martin, Douglas R.
Publicado no ASN Neuro (2015)

AAVrh10 Gene Therapy Ameliorates Central and Peripheral Nervous System Disease in Canine Globoid Cell Leukodystrophy (Krabbe Disease)

Por Bradbury, Allison M., Rafi, Mohammed A., Bagel, Jessica H., Brisson, Becky K., Marshall, Michael S., Pesayco Salvador, Jill, Jiang, Xuntain, Swain, Gary P., Prociuk, Maria L., ODonnell, Patricia A., Fitzgerald, Caitlin, Ory, Daniel S., Bongarzone, Ernesto R., Shelton, G. Diane, Wenger, David A., Vite, Charles H.
Publicado no Hum Gene Ther (2018)

AAV Mediated Gene Delivery Attenuates Neuroinflammation in Feline Sandhoff Disease

Por Bradbury, Allison M, Peterson, Tiffany A, Gross, Amanda L, Wells, Stephen Z, McCurdy, Victoria J, Wolfe, Karen G, Dennis, John C, Brunson, Brandon L, Gray-Edwards, Heather, Randle, Ashley N, Johnson, Aime K, Morrison, Edward E, Cox, Nancy R, Baker, Henry J, Sena-Esteves, Miguel, Martin, Douglas R
Publicado no Neuroscience (2016)

Direct Intracranial Injection of AAVrh8 Encoding Monkey β-N-Acetylhexosaminidase Causes Neurotoxicity in the Primate Brain

Por Golebiowski, Diane, van der Bom, Imramsjah M.J., Kwon, Churl-Su, Miller, Andrew D., Petrosky, Keiko, Bradbury, Allison M., Maitland, Stacy, Kühn, Anna Luisa, Bishop, Nina, Curran, Elizabeth, Silva, Nilsa, GuhaSarkar, Dwijit, Westmoreland, Susan V., Martin, Douglas R., Gounis, Matthew J., Asaad, Wael F., Sena-Esteves, Miguel
Publicado no Hum Gene Ther (2017)

Therapeutic Response in Feline Sandhoff Disease Despite Immunity to Intracranial Gene Therapy

Por Bradbury, Allison M, Cochran, J Nicholas, McCurdy, Victoria J, Johnson, Aime K, Brunson, Brandon L, Gray-Edwards, Heather, Leroy, Stanley G, Hwang, Misako, Randle, Ashley N, Jackson, Laura S, Morrison, Nancy E, Baek, Rena C, Seyfried, Thomas N, Cheng, Seng H, Cox, Nancy R, Baker, Henry J, Cachón-González, M Begona, Cox, Timothy M, Sena-Esteves, Miguel, Martin, Douglas R
Publicado em 2013

Biomarkers for disease progression and AAV therapeutic efficacy in feline Sandhoff disease

Por Bradbury, Allison M, Gray-Edwards, Heather L, Shirley, Jamie L, McCurdy, Victoria J, Colaco, Alexandria N, Randle, Ashley N, Christopherson, Pete W, Bird, Allison C, Johnson, Aime K, Wilson, Diane U, Hudson, Judith A, De Pompa, Nicholas L, Sorjonen, Donald C, Brunson, Brandon L, Jeyakumar, Mylvaganam, Platt, Frances M, Baker, Henry J, Cox, Nancy R, Sena-Esteves, Miguel, Martin, Douglas R
Publicado no Exp Neurol (2014)

Novel Biomarkers of Human GM1 Gangliosidosis Reflect the Clinical Efficacy of Gene Therapy in a Feline Model

Por Gray-Edwards, Heather L., Regier, Debra S., Shirley, Jamie L., Randle, Ashley N., Salibi, Nouha, Thomas, Sarah E., Latour, Yvonne L., Johnston, Jean, Golas, Gretchen, Maguire, Annie S., Taylor, Amanda R., Sorjonen, Donald C., McCurdy, Victoria J., Christopherson, Peter W., Bradbury, Allison M., Beyers, Ronald J., Johnson, Aime K., Brunson, Brandon L., Cox, Nancy R., Baker, Henry J., Denney, Thomas S., Sena-Esteves, Miguel, Tifft, Cynthia J., Martin, Douglas R.
Publicado no Mol Ther (2017)