The Antioxidant N-Acetylcysteine Prevents HIF-1 Stabilization under Hypoxia In Vitro but Does Not Affect Tumorigenesis in Multiple Breast Cancer Models In Vivo

Por Sceneay, Jaclyn, Liu, Mira C. P., Chen, Anna, Wong, Christina S. F., Bowtell, David D. L., Möller, Andreas
Publicado em 2013

A Mouse with a Loss-of-function Mutation in the c-Cbl TKB Domain Shows Perturbed Thymocyte Signaling without Enhancing the Activity of the ZAP-70 Tyrosine Kinase

Por Thien, Christine B.F., Scaife, Robin M., Papadimitriou, John M., Murphy, Maria A., Bowtell, David D.L., Langdon, Wallace Y.
Publicado em 2003

Stress-induced decrease in TRAF2 stability is mediated by Siah2

Por Habelhah, Hasem, Frew, Ian J., Laine, Aaron, Janes, Peter W., Relaix, Frederic, Sassoon, David, Bowtell, David D.L., Ronai, Ze’ev
Publicado em 2002

A binding motif for Siah ubiquitin ligase

Por House, Colin M., Frew, Ian J., Huang, Huei-Luen, Wiche, Gerhard, Traficante, Nadia, Nice, Edouard, Catimel, Bruno, Bowtell, David D. L.
Publicado em 2003

Amplicon-Dependent CCNE1 Expression Is Critical for Clonogenic Survival after Cisplatin Treatment and Is Correlated with 20q11 Gain in Ovarian Cancer

Por Etemadmoghadam, Dariush, George, Joshy, Cowin, Prue A., Cullinane, Carleen, Kansara, Maya, Gorringe, Kylie L., Smyth, Gordon K., Bowtell, David D. L.
Publicado em 2010

Normal p53 Function in Primary Cells Deficient for Siah Genes

Por Frew, Ian J., Dickins, Ross A., Cuddihy, Andrew R., Del Rosario, Merci, Reinhard, Christoph, O'Connell, Matthew J., Bowtell, David D. L.
Publicado em 2002

Inhibition of Siah ubiquitin ligase function

Por Möller, Andreas, House, Colin M., Wong, Christina S.F., Scanlon, Denis B., Liu, Mira C.P., Ronai, Ze’ev, Bowtell, David D.L.
Publicado em 2008

Tissue Hyperplasia and Enhanced T-Cell Signalling via ZAP-70 in c-Cbl-Deficient Mice

Por Murphy, Maria A., Schnall, Ralf G., Venter, Deon J., Barnett, Louise, Bertoncello, Ivan, Thien, Christine B. F., Langdon, Wallace Y., Bowtell, David D. L.
Publicado em 1998

Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube derived high-grade serous ovarian cancers

Por Karst, Alison M., Jones, Paul M., Vena, Natalie, Ligon, Azra H., Liu, Joyce F., Hirsch, Michelle S., Etemadmoghadam, Dariush, Bowtell, David D. L., Drapkin, Ronny
Publicado no Cancer Res (2013)

The Cbl Proto-Oncogene Product Negatively Regulates the Src-Family Tyrosine Kinase Fyn by Enhancing Its Degradation

Por Andoniou, Christopher E., Lill, Nancy L., Thien, Christine B., Lupher, Mark L., Ota, Satoshi, Bowtell, David D. L., Scaife, Robin M., Langdon, Wallace Y., Band, Hamid
Publicado em 2000

The Ubiquitin Ligase Component Siah1a Is Required for Completion of Meiosis I in Male Mice

Por Dickins, Ross A., Frew, Ian J., House, Colin M., O'Bryan, Moira K., Holloway, Andrew J., Haviv, Izhak, Traficante, Nadia, de Kretser, David M., Bowtell, David D. L.
Publicado em 2002

Synthetic lethality between CCNE1 amplification and loss of BRCA1

Por Etemadmoghadam, Dariush, Weir, Barbara A., Au-Yeung, George, Alsop, Kathryn, Mitchell, Gillian, George, Joshy, Davis, Sally, D’Andrea, Alan D., Simpson, Kaylene, Hahn, William C., Bowtell, David D. L.
Publicado em 2013

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

Por Ryland, Georgina L., Hunter, Sally M., Doyle, Maria A., Caramia, Franco, Li, Jason, Rowley, Simone M., Christie, Michael, Allan, Prue E., Stephens, Andrew N., Bowtell, David D L, Campbell, Ian G., Gorringe, Kylie L.
Publicado no Genome Med (2015)

Erratum to: Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

Por Ryland, Georgina L., Hunter, Sally M., Doyle, Maria A., Caramia, Franco, Li, Jason, Rowley, Simone M., Christie, Michael, Allan, Prue E., Stephens, Andrew N., Bowtell, David D. L., Campbell, Ian G., Gorringe, Kylie L.
Publicado no Genome Med (2017)

c-Cbl–deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action

Por Molero, Juan C., Jensen, Thomas E., Withers, Phil C., Couzens, Michelle, Herzog, Herbert, Thien, Christine B.F., Langdon, Wallace Y., Walder, Ken, Murphy, Maria A., Bowtell, David D.L., James, David E., Cooney, Gregory J.
Publicado em 2004

Activation of YAP1 Is Associated with Poor Prognosis and Response to Taxanes in Ovarian Cancer

Por Jeong, Woojin, Kim, Sang-Bae, Sohn, Bo Hwa, Park, Yun-Yong, Park, Eun Sung, Kim, Sang Cheol, Kim, Sung Soo, Johnson, Randy L., Birrer, Michael, Bowtell, David S. L., Mills, Gordon B., Sood, Anil, Lee, Ju-Seog
Publicado em 2014

Copy Number Analysis Identifies Novel Interactions Between Genomic Loci in Ovarian Cancer

Por Gorringe, Kylie L., George, Joshy, Anglesio, Michael S., Ramakrishna, Manasa, Etemadmoghadam, Dariush, Cowin, Prue, Sridhar, Anita, Williams, Louise H., Boyle, Samantha E., Yanaihara, Nozomu, Okamoto, Aikou, Urashima, Mitsuyoshi, Smyth, Gordon K., Campbell, Ian G., Bowtell, David D. L.
Publicado em 2010

c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action

Por Molero, Juan C., Jensen, Thomas E., Withers, Phil C., Couzens, Michelle, Herzog, Herbert, Thien, Christine B.F., Langdon, Wallace Y., Walder, Ken, Murphy, Maria A., Bowtell, David D.L., Hardeman, Edna, Ghoddusi, Majid, James, David E., Cooney, Gregory J.
Publicado em 2005

Comparison of Expression Profiles in Ovarian Epithelium In Vivo and Ovarian Cancer Identifies Novel Candidate Genes Involved in Disease Pathogenesis

Por Emmanuel, Catherine, Gava, Natalie, Kennedy, Catherine, Balleine, Rosemary L., Sharma, Raghwa, Wain, Gerard, Brand, Alison, Hogg, Russell, Etemadmoghadam, Dariush, George, Joshy, Birrer, Michael J., Clarke, Christine L., Chenevix-Trench, Georgia, Bowtell, David D. L., Harnett, Paul R., deFazio, Anna
Publicado em 2011

High Levels of Genomic Aberrations in Serous Ovarian Cancers Are Associated with Better Survival

Por Baumbusch, Lars O., Helland, Åslaug, Wang, Yun, Liestøl, Knut, Schaner, Marci E., Holm, Ruth, Etemadmoghadam, Dariush, Alsop, Kathryn, Brown, Pat, Mitchell, Gillian, Fereday, Sian, DeFazio, Anna, Bowtell, David D. L., Kristensen, Gunnar B., Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise
Publicado em 2013