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Activation of YAP1 Is Associated with Poor Prognosis and Response to Taxanes in Ovarian Cancer

AIM: We aimed to investigate the clinical significance of the activation of Yes-Associated Protein 1 (YAP1), a key downstream effector of Hippo tumor-suppressor pathway, in ovarian cancer. PATIENTS AND METHODS: A gene expression signature reflecting activation of YAP1 was developed from gene express...

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Detalhes bibliográficos
Main Authors: Jeong, Woojin, Kim, Sang-Bae, Sohn, Bo Hwa, Park, Yun-Yong, Park, Eun Sung, Kim, Sang Cheol, Kim, Sung Soo, Johnson, Randy L., Birrer, Michael, Bowtell, David S. L., Mills, Gordon B., Sood, Anil, Lee, Ju-Seog
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082822/
https://ncbi.nlm.nih.gov/pubmed/24511017
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