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Significant Association of oncogene YAP1 with Poor Prognosis and Cetuximab Resistance in Colorectal Cancer Patients

PURPOSE: Activation of YAP1, novel oncogene in Hippo pathway, has been observed in many cancers including colorectal cancer (CRC). We investigated if activation of YAP1 is significantly associated with prognosis or treatment outcomes in CRC EXPERIMENTAL DESIGN: A gene expression signature reflecting...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Lee, Keun-Wook, Lee, Sung Sook, Kim, Sang-Bae, Sohn, Bo Hwa, Lee, Hyun-Sung, Jang, Hee-Jin, Park, Yun-Yong, Kopetz, Scott, Kim, Sung Soo, Oh, Sang Cheul, Lee, Ju-Seog
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513664/
https://ncbi.nlm.nih.gov/pubmed/25388162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1374
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