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Significant Association of oncogene YAP1 with Poor Prognosis and Cetuximab Resistance in Colorectal Cancer Patients

PURPOSE: Activation of YAP1, novel oncogene in Hippo pathway, has been observed in many cancers including colorectal cancer (CRC). We investigated if activation of YAP1 is significantly associated with prognosis or treatment outcomes in CRC EXPERIMENTAL DESIGN: A gene expression signature reflecting...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Lee, Keun-Wook, Lee, Sung Sook, Kim, Sang-Bae, Sohn, Bo Hwa, Lee, Hyun-Sung, Jang, Hee-Jin, Park, Yun-Yong, Kopetz, Scott, Kim, Sung Soo, Oh, Sang Cheul, Lee, Ju-Seog
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513664/
https://ncbi.nlm.nih.gov/pubmed/25388162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1374
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