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Significant Association of oncogene YAP1 with Poor Prognosis and Cetuximab Resistance in Colorectal Cancer Patients

PURPOSE: Activation of YAP1, novel oncogene in Hippo pathway, has been observed in many cancers including colorectal cancer (CRC). We investigated if activation of YAP1 is significantly associated with prognosis or treatment outcomes in CRC EXPERIMENTAL DESIGN: A gene expression signature reflecting...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Lee, Keun-Wook, Lee, Sung Sook, Kim, Sang-Bae, Sohn, Bo Hwa, Lee, Hyun-Sung, Jang, Hee-Jin, Park, Yun-Yong, Kopetz, Scott, Kim, Sung Soo, Oh, Sang Cheul, Lee, Ju-Seog
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513664/
https://ncbi.nlm.nih.gov/pubmed/25388162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1374
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