Inactivation of Hippo pathway is significantly associated with poor prognosis in hepatocellular carcinoma

PURPOSE: The Hippo pathway is a tumor suppressor in the liver. However, the clinical significance of Hippo pathway inactivation in HCC is not clearly defined. We analyzed genomic data from human and mouse tissues to determine clinical relevance of Hippo pathway inactivation in HCC. EXPERIMENTAL DESI...

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Publicado en:Clin Cancer Res
Main Authors: Sohn, Bo Hwa, Shim, Jae-Jun, Kim, Sang-Bae, Jang, Kyu Yun, Kim, Soo Mi, Kim, Ji Hoon, Hwang, Jun Eul, Jang, Hee-Jin, Lee, Hyun-Sung, Kim, Sang-Cheol, Jeong, Woojin, Kim, Sung Soo, Park, Eun Sung, Heo, Jeonghoon, Kim, Yoon Jun, Kim, Dae-Ghon, Leem, Sun-Hee, Kaseb, Ahmed, Hassan, Manal M., Cha, Minse, Chu, In-Sun, Johnson, Randy L., Park, Yun-Yong, Lee, Ju-Seog
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536176/
https://ncbi.nlm.nih.gov/pubmed/26459179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-1447
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