Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers

Immunotherapy has emerged as a promising anti-cancer treatment, however, little is known about the genetic characteristics that dictate response to immunotherapy. We develop a transcriptional predictor of immunotherapy response and assess its prediction in genomic data from ~10,000 human tissues acr...

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Publicat a:Nat Commun
Autors principals: Ock, Chan-Young, Hwang, Jun-Eul, Keam, Bhumsuk, Kim, Sang-Bae, Shim, Jae-Jun, Jang, Hee-Jin, Park, Sarang, Sohn, Bo Hwa, Cha, Minse, Ajani, Jaffer A., Kopetz, Scott, Lee, Keun-Wook, Kim, Tae Min, Heo, Dae Seog, Lee, Ju-Seog
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648801/
https://ncbi.nlm.nih.gov/pubmed/29051489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01018-0
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