YAP1 and TAZ Activates mTORC1 Pathway by Regulating Amino Acid Transporters in hepatocellular carcinoma

Metabolic activation is a common feature of many cancer cells and is frequently associated with the clinical outcomes of various cancers, including hepatocellular carcinoma (HCC). Thus, aberrantly activated metabolic pathways in cancer cells are attractive targets for cancer therapy. YAP1 and TAZ ar...

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Pubblicato in:Hepatology
Autori principali: Park, Yun-Yong, Sohn, Bo Hwa, Johnson, Randy L., Kang, Myoung-Hee, Kim, Sang Bae, Shim, Jae-Jun, Mangala, Lingegowda S., Kim, Ji Hoon, Yoo, Jeong Eun, Rodriguez-Aguayo, Cristian, Pradeep, Sunila, Hwang, Jun Eul, Jang, Hee-Jin, Lee, Hyun-Sung, Rupaimoole, Rajesha, Lopez-Berestein, Gabriel, Jeong, Woojin, Park, Inn Sun, Park, Young Nyun, Sood, Anil K., Mills, Gordon B., Lee, Ju-Seog
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881866/
https://ncbi.nlm.nih.gov/pubmed/26389641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28223
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