YAP1 and TAZ Activates mTORC1 Pathway by Regulating Amino Acid Transporters in hepatocellular carcinoma

Metabolic activation is a common feature of many cancer cells and is frequently associated with the clinical outcomes of various cancers, including hepatocellular carcinoma (HCC). Thus, aberrantly activated metabolic pathways in cancer cells are attractive targets for cancer therapy. YAP1 and TAZ ar...

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Bibliographic Details
Published in:Hepatology
Main Authors: Park, Yun-Yong, Sohn, Bo Hwa, Johnson, Randy L., Kang, Myoung-Hee, Kim, Sang Bae, Shim, Jae-Jun, Mangala, Lingegowda S., Kim, Ji Hoon, Yoo, Jeong Eun, Rodriguez-Aguayo, Cristian, Pradeep, Sunila, Hwang, Jun Eul, Jang, Hee-Jin, Lee, Hyun-Sung, Rupaimoole, Rajesha, Lopez-Berestein, Gabriel, Jeong, Woojin, Park, Inn Sun, Park, Young Nyun, Sood, Anil K., Mills, Gordon B., Lee, Ju-Seog
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881866/
https://ncbi.nlm.nih.gov/pubmed/26389641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28223
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