Central role of mTORC1 downstream of YAP/TAZ in hepatoblastoma development

Hepatoblastoma (HB) is the most common type of liver malignancy in children. Recent studies suggest that activation of Yes-associated protein (YAP) is a major molecular event in HB development, as activated YAP synergizes with mutant β-catenin to promote HB formation in mice (YAP/β-catenin). However...

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Vydáno v:Oncotarget
Hlavní autoři: Liu, Pin, Calvisi, Diego F., Kiss, Andras, Cigliano, Antonio, Schaff, Zsuzsa, Che, Li, Ribback, Silvia, Dombrowski, Frank, Zhao, Dongchi, Chen, Xin
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
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Priority Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650273/
https://ncbi.nlm.nih.gov/pubmed/29088718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20622
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