Activation of β Catenin and Yap1 in Human Hepatoblastoma and Induction of Hepatocarcinogenesis in Mice

BACKGROUND & AIMS: Aberrant activation of βcatenin and Yes-associated protein 1 (Yap1) signaling pathways have been associated with development of multiple tumor types. Yap functions as a transcriptional co-activator by interacting with TEAD DNA binding proteins. We investigated the interactions...

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Main Authors: Tao, Junyan, Calvisi, Diego F., Ranganathan, Sarangarajan, Cigliano, Antonio, Zhou, Lili, Singh, Sucha, Jiang, Lijie, Fan, Biao, Terracciano, Luigi, Armeanu-Ebinger, Sorin, Ribback, Silvia, Dombrowski, Frank, Evert, Matthias, Chen, Xin, Monga, Satdarshan P. S.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143445/
https://ncbi.nlm.nih.gov/pubmed/24837480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.05.004
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