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Yap/Taz mediates mTORC2-stimulated fibroblast activation and kidney fibrosis
Our previously published study demonstrated that mammalian target of rapamycin complex 2 (mTORC2) signaling mediates TGFβ1-induced fibroblast activation. However, the underlying mechanisms for mTORC2 in stimulating fibroblast activation remain poorly understood. Here, we found that TGFβ1 could stimu...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6200934/ https://ncbi.nlm.nih.gov/pubmed/30154246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004073 |
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