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Loss of Rictor in tubular cells exaggerates lipopolysaccharide induced renal inflammation and acute kidney injury via Yap/Taz-NF-κB axis

Our previous study demonstrated that the mammalian target of rapamycin complex 2 (mTORC2) signaling alleviates renal inflammation and protects against cisplatin-induced AKI. However, the underlying mechanisms for mTORC2 in regulating renal inflammation in AKI remain to be determined. In this study,...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Gui, Yuan, Hou, Qing, Lu, Qingmiao, Dai, Chunsun, Li, Jianzhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260239/
https://ncbi.nlm.nih.gov/pubmed/32528729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-020-0274-3
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