Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

Osteoarthritis is one of the leading causes of pain and disability in the aged population due to articular cartilage damage. This warrants investigation of signaling mechanisms that could protect cartilage from degeneration and degradation. Here we show in a murine model of experimental osteoarthrit...

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Vydáno v:Nat Commun
Hlavní autoři: Deng, Yujie, Lu, Jinqiu, Li, Wenling, Wu, Ailing, Zhang, Xu, Tong, Wenxue, Ho, Kiwai Kevin, Qin, Ling, Song, Hai, Mak, Kinglun Kingston
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212432/
https://ncbi.nlm.nih.gov/pubmed/30385786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07022-2
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