Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation

Osteoarthritis is one of the leading causes of pain and disability in the aged population due to articular cartilage damage. This warrants investigation of signaling mechanisms that could protect cartilage from degeneration and degradation. Here we show in a murine model of experimental osteoarthrit...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Deng, Yujie, Lu, Jinqiu, Li, Wenling, Wu, Ailing, Zhang, Xu, Tong, Wenxue, Ho, Kiwai Kevin, Qin, Ling, Song, Hai, Mak, Kinglun Kingston
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6212432/
https://ncbi.nlm.nih.gov/pubmed/30385786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07022-2
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