Reciprocal regulation of YAP/TAZ by the Hippo pathway and the Small GTPase pathway

Yes-associated protein 1 (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) (YAP/TAZ) are transcriptional coactivators that regulate genes involved in proliferation and transformation by interacting with DNA-binding transcription factors. Remarkably, YAP/TAZ are essential for cancer...

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Bibliographic Details
Published in:Small GTPases
Main Authors: Jang, Ju-Won, Kim, Min-Kyu, Bae, Suk-Chul
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
Subjects:
Mini-Review - Commissioned
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549623/
https://ncbi.nlm.nih.gov/pubmed/29457552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2018.1435986
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