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PRMT5 inhibition attenuates cartilage degradation by reducing MAPK and NF-κB signaling
OBJECTIVES: A role for the type II arginine methyltransferase PRMT5 in various human diseases has been identified. In this study, the potential mechanism underlying the involvement of PRMT5 in the pathological process leading to osteoarthritis (OA) was investigated. METHODS: PRMT5 expression in cart...
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| Publicado no: | Arthritis Res Ther |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7650297/ https://ncbi.nlm.nih.gov/pubmed/32887644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02304-x |
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