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Blockade of NF-κB and MAPK pathways by ulinastatin attenuates wear particle-stimulated osteoclast differentiation in vitro and in vivo
Ulinastatin, a urinary trypsin inhibitor (UTI), is widely used to clinically treat lipopolysaccharide (LPS)-related inflammatory disorders recently. Adherent pathogen-associated molecular patterns (PAMPs), of which LPS is the best-studied and classical endotoxin produced by Gram-negative bacteria, a...
में बचाया:
में प्रकाशित: | Biosci Rep |
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मुख्य लेखकों: | , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Portland Press Ltd.
2016
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5091469/ https://ncbi.nlm.nih.gov/pubmed/27638499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160234 |
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