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PRMT5 inhibition attenuates cartilage degradation by reducing MAPK and NF-κB signaling
OBJECTIVES: A role for the type II arginine methyltransferase PRMT5 in various human diseases has been identified. In this study, the potential mechanism underlying the involvement of PRMT5 in the pathological process leading to osteoarthritis (OA) was investigated. METHODS: PRMT5 expression in cart...
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| 出版年: | Arthritis Res Ther |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7650297/ https://ncbi.nlm.nih.gov/pubmed/32887644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02304-x |
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