Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and Fibrosis

Ras homolog enriched in brain (Rheb) is a small GTPase that regulates cell growth, differentiation, and survival by upregulating mammalian target of rapamycin complex 1 (mTORC1) signaling. The role of Rheb/mTORC1 signaling in the activation of kidney fibroblasts and the development of kidney fibrosi...

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Dettagli Bibliografici
Autori principali: Jiang, Lei, Xu, Lingling, Mao, Junhua, Li, Jianzhong, Fang, Li, Zhou, Yang, Liu, Wei, He, Weichun, Zhao, Allan Zijian, Yang, Junwei, Dai, Chunsun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2013
Soggetti:
Basic Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699820/
https://ncbi.nlm.nih.gov/pubmed/23661807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012050476
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