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Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and Fibrosis
Ras homolog enriched in brain (Rheb) is a small GTPase that regulates cell growth, differentiation, and survival by upregulating mammalian target of rapamycin complex 1 (mTORC1) signaling. The role of Rheb/mTORC1 signaling in the activation of kidney fibroblasts and the development of kidney fibrosi...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Nephrology
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3699820/ https://ncbi.nlm.nih.gov/pubmed/23661807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012050476 |
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