Calmodulin-dependent Protein Kinase II/cAMP Response Element-binding Protein/Wnt/β-Catenin Signaling Cascade Regulates Angiotensin II-induced Podocyte Injury and Albuminuria

Angiotensin II (Ang II) plays a pivotal role in promoting podocyte dysfunction and albuminuria, however, the underlying mechanisms have not been fully delineated. In this study, we found that Ang II induced Wnt1 expression and β-catenin nuclear translocation in cultured mouse podocytes. Blocking Wnt...

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Autors principals: Jiang, Lei, Xu, Lingling, Song, Yuxian, Li, Jianzhong, Mao, Junhua, Zhao, Allan Zijian, He, Weichun, Yang, Junwei, Dai, Chunsun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743506/
https://ncbi.nlm.nih.gov/pubmed/23803607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460394
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