Wnt/β-Catenin Signaling Promotes Podocyte Dysfunction and Albuminuria

Podocyte dysfunction, one of the major causes of proteinuria, leads to glomerulosclerosis and end stage renal disease, but its underlying mechanism remains poorly understood. Here we show that Wnt/β-catenin signaling plays a critical role in podocyte injury and proteinuria. Treatment with adriamycin...

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Détails bibliographiques
Auteurs principaux: Dai, Chunsun, Stolz, Donna B., Kiss, Lawrence P., Monga, Satdarshan P., Holzman, Lawrence B., Liu, Youhua
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2009
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736766/
https://ncbi.nlm.nih.gov/pubmed/19628668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009010019
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