Wnt/β-Catenin Signaling Promotes Podocyte Dysfunction and Albuminuria

Podocyte dysfunction, one of the major causes of proteinuria, leads to glomerulosclerosis and end stage renal disease, but its underlying mechanism remains poorly understood. Here we show that Wnt/β-catenin signaling plays a critical role in podocyte injury and proteinuria. Treatment with adriamycin...

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Detalhes bibliográficos
Main Authors: Dai, Chunsun, Stolz, Donna B., Kiss, Lawrence P., Monga, Satdarshan P., Holzman, Lawrence B., Liu, Youhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2009
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736766/
https://ncbi.nlm.nih.gov/pubmed/19628668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009010019
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