Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and Fibrosis

Ras homolog enriched in brain (Rheb) is a small GTPase that regulates cell growth, differentiation, and survival by upregulating mammalian target of rapamycin complex 1 (mTORC1) signaling. The role of Rheb/mTORC1 signaling in the activation of kidney fibroblasts and the development of kidney fibrosi...

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Bibliographic Details
Main Authors:	Jiang, Lei, Xu, Lingling, Mao, Junhua, Li, Jianzhong, Fang, Li, Zhou, Yang, Liu, Wei, He, Weichun, Zhao, Allan Zijian, Yang, Junwei, Dai, Chunsun
Format:	Artigo
Language:	Inglês
Published:	American Society of Nephrology 2013
Subjects:	Basic Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3699820/ https://ncbi.nlm.nih.gov/pubmed/23661807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012050476
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Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and Fibrosis

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