The Clinicopathological Significance of YAP/TAZ Expression in Hepatocellular Carcinoma with Relation to Hypoxia and Stemness

Background/Aims: Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) activation has been implicated in hepatocarcinogenesis and hepatic progenitor cell differentiation, and hypoxia has been shown to induce nuclear translocation of YAP in cancer cells. Here, we...

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Veröffentlicht in:Pathol Oncol Res
Hauptverfasser: Park, Hyunjin, Lee, Yangkyu, Lee, Kiryang, Lee, Hyejung, Yoo, Jeong Eun, Ahn, Soomin, Park, Young Nyun, Kim, Haeryoung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Society Journal Archive
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8262240/
https://ncbi.nlm.nih.gov/pubmed/34257565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/pore.2021.604600
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