Normal p53 Function in Primary Cells Deficient for Siah Genes

Overexpression studies have suggested that Siah1 proteins may act as effectors of p53-mediated cellular responses and as regulators of mitotic progression. We have tested these hypotheses using Siah gene knockout mice. Siah1a and Siah1b were not induced by activation of endogenous p53 in tissues, pr...

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Detalhes bibliográficos
Main Authors: Frew, Ian J., Dickins, Ross A., Cuddihy, Andrew R., Del Rosario, Merci, Reinhard, Christoph, O'Connell, Matthew J., Bowtell, David D. L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC134066/
https://ncbi.nlm.nih.gov/pubmed/12417719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8155-8164.2002
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