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Normal p53 Function in Primary Cells Deficient for Siah Genes

Overexpression studies have suggested that Siah1 proteins may act as effectors of p53-mediated cellular responses and as regulators of mitotic progression. We have tested these hypotheses using Siah gene knockout mice. Siah1a and Siah1b were not induced by activation of endogenous p53 in tissues, pr...

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Bibliografische gegevens
Hoofdauteurs: Frew, Ian J., Dickins, Ross A., Cuddihy, Andrew R., Del Rosario, Merci, Reinhard, Christoph, O'Connell, Matthew J., Bowtell, David D. L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC134066/
https://ncbi.nlm.nih.gov/pubmed/12417719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8155-8164.2002
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