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Normal p53 Function in Primary Cells Deficient for Siah Genes
Overexpression studies have suggested that Siah1 proteins may act as effectors of p53-mediated cellular responses and as regulators of mitotic progression. We have tested these hypotheses using Siah gene knockout mice. Siah1a and Siah1b were not induced by activation of endogenous p53 in tissues, pr...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134066/ https://ncbi.nlm.nih.gov/pubmed/12417719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8155-8164.2002 |
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