Generation and Analysis of Siah2 Mutant Mice

Siah proteins function as E3 ubiquitin ligase enzymes to target the degradation of diverse protein substrates. To characterize the physiological roles of Siah2, we have generated and analyzed Siah2 mutant mice. In contrast to Siah1a knockout mice, which are growth retarded and exhibit defects in spe...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Frew, Ian J., Hammond, Vicki E., Dickins, Ross A., Quinn, Julian M. W., Walkley, Carl R., Sims, Natalie A., Schnall, Ralf, Della, Neil G., Holloway, Andrew J., Digby, Matthew R., Janes, Peter W., Tarlinton, David M., Purton, Louise E., Gillespie, Matthew T., Bowtell, David D. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2003
Schlagworte:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309644/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14645526/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.24.9150-9161.2003
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