Generation and Analysis of Siah2 Mutant Mice

Siah proteins function as E3 ubiquitin ligase enzymes to target the degradation of diverse protein substrates. To characterize the physiological roles of Siah2, we have generated and analyzed Siah2 mutant mice. In contrast to Siah1a knockout mice, which are growth retarded and exhibit defects in spe...

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Auteurs principaux: Frew, Ian J., Hammond, Vicki E., Dickins, Ross A., Quinn, Julian M. W., Walkley, Carl R., Sims, Natalie A., Schnall, Ralf, Della, Neil G., Holloway, Andrew J., Digby, Matthew R., Janes, Peter W., Tarlinton, David M., Purton, Louise E., Gillespie, Matthew T., Bowtell, David D. L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
Sujets:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC309644/
https://ncbi.nlm.nih.gov/pubmed/14645526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.24.9150-9161.2003
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