Normal p53 Function in Primary Cells Deficient for Siah Genes

Overexpression studies have suggested that Siah1 proteins may act as effectors of p53-mediated cellular responses and as regulators of mitotic progression. We have tested these hypotheses using Siah gene knockout mice. Siah1a and Siah1b were not induced by activation of endogenous p53 in tissues, pr...

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Bibliografske podrobnosti
Main Authors: Frew, Ian J., Dickins, Ross A., Cuddihy, Andrew R., Del Rosario, Merci, Reinhard, Christoph, O'Connell, Matthew J., Bowtell, David D. L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Cell Growth and Development
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC134066/
https://ncbi.nlm.nih.gov/pubmed/12417719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8155-8164.2002
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