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Normal p53 Function in Primary Cells Deficient for Siah Genes

Overexpression studies have suggested that Siah1 proteins may act as effectors of p53-mediated cellular responses and as regulators of mitotic progression. We have tested these hypotheses using Siah gene knockout mice. Siah1a and Siah1b were not induced by activation of endogenous p53 in tissues, pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Frew, Ian J., Dickins, Ross A., Cuddihy, Andrew R., Del Rosario, Merci, Reinhard, Christoph, O'Connell, Matthew J., Bowtell, David D. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC134066/
https://ncbi.nlm.nih.gov/pubmed/12417719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8155-8164.2002
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