Analysis of ku80-Mutant Mice and Cells with Deficient Levels of p53

Absence of Ku80 results in increased sensitivity to ionizing radiation, defective lymphocyte development, early onset of an age-related phenotype, and premature replicative senescence. Here we investigate the role of p53 on the phenotype of ku80-mutant mice and cells. Reducing levels of p53 increase...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Lim, Dae-Sik, Vogel, Hannes, Willerford, Dennis M., Sands, Arthur T., Platt, Kenneth A., Hasty, Paul
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10805721/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.11.3772-3780.2000
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