Treatment Strategies for ARID1A-Deficient Ovarian Clear Cell Carcinoma

por Takahashi, Kazuaki, Takenaka, Masataka, Okamoto, Aikou, Bowtell, David D. L., Kohno, Takashi
Publicado en Cancers (Basel) (2021)

Mechanisms and clinical implications of tumor heterogeneity and convergence on recurrent phenotypes

por McQuerry, Jasmine A., Chang, Jeffrey T., Bowtell, David D. L., Cohen, Adam, Bild, Andrea H.
Publicado en J Mol Med (Berl) (2017)

The Antioxidant N-Acetylcysteine Prevents HIF-1 Stabilization under Hypoxia In Vitro but Does Not Affect Tumorigenesis in Multiple Breast Cancer Models In Vivo

por Sceneay, Jaclyn, Liu, Mira C. P., Chen, Anna, Wong, Christina S. F., Bowtell, David D. L., Möller, Andreas
Publicado 2013

A Mouse with a Loss-of-function Mutation in the c-Cbl TKB Domain Shows Perturbed Thymocyte Signaling without Enhancing the Activity of the ZAP-70 Tyrosine Kinase

por Thien, Christine B.F., Scaife, Robin M., Papadimitriou, John M., Murphy, Maria A., Bowtell, David D.L., Langdon, Wallace Y.
Publicado 2003

Stress-induced decrease in TRAF2 stability is mediated by Siah2

por Habelhah, Hasem, Frew, Ian J., Laine, Aaron, Janes, Peter W., Relaix, Frederic, Sassoon, David, Bowtell, David D.L., Ronai, Ze’ev
Publicado 2002

A binding motif for Siah ubiquitin ligase

por House, Colin M., Frew, Ian J., Huang, Huei-Luen, Wiche, Gerhard, Traficante, Nadia, Nice, Edouard, Catimel, Bruno, Bowtell, David D. L.
Publicado 2003

Amplicon-Dependent CCNE1 Expression Is Critical for Clonogenic Survival after Cisplatin Treatment and Is Correlated with 20q11 Gain in Ovarian Cancer

por Etemadmoghadam, Dariush, George, Joshy, Cowin, Prue A., Cullinane, Carleen, Kansara, Maya, Gorringe, Kylie L., Smyth, Gordon K., Bowtell, David D. L.
Publicado 2010

Chemotherapy weakly contributes to predicted neoantigen expression in ovarian cancer

por O’Donnell, Timothy, Christie, Elizabeth L., Ahuja, Arun, Buros, Jacqueline, Aksoy, B. Arman, Bowtell, David D. L., Snyder, Alexandra, Hammerbacher, Jeff
Publicado en BMC Cancer (2018)

Normal p53 Function in Primary Cells Deficient for Siah Genes

por Frew, Ian J., Dickins, Ross A., Cuddihy, Andrew R., Del Rosario, Merci, Reinhard, Christoph, O'Connell, Matthew J., Bowtell, David D. L.
Publicado 2002

Inhibition of Siah ubiquitin ligase function

por Möller, Andreas, House, Colin M., Wong, Christina S.F., Scanlon, Denis B., Liu, Mira C.P., Ronai, Ze’ev, Bowtell, David D.L.
Publicado 2008

Tissue Hyperplasia and Enhanced T-Cell Signalling via ZAP-70 in c-Cbl-Deficient Mice

por Murphy, Maria A., Schnall, Ralf G., Venter, Deon J., Barnett, Louise, Bertoncello, Ivan, Thien, Christine B. F., Langdon, Wallace Y., Bowtell, David D. L.
Publicado 1998

Cyclin E1 deregulation occurs early in secretory cell transformation to promote formation of fallopian tube derived high-grade serous ovarian cancers

por Karst, Alison M., Jones, Paul M., Vena, Natalie, Ligon, Azra H., Liu, Joyce F., Hirsch, Michelle S., Etemadmoghadam, Dariush, Bowtell, David D. L., Drapkin, Ronny
Publicado en Cancer Res (2013)

Germline whole exome sequencing of a family with appendiceal mucinous tumours presenting with pseudomyxoma peritonei

por Lung, Mei Sim, Mitchell, Catherine A., Doyle, Maria A., Lynch, Andrew C., Gorringe, Kylie L., Bowtell, David D. L., Campbell, Ian G., Trainer, Alison H.
Publicado en BMC Cancer (2020)

The Cbl Proto-Oncogene Product Negatively Regulates the Src-Family Tyrosine Kinase Fyn by Enhancing Its Degradation

por Andoniou, Christopher E., Lill, Nancy L., Thien, Christine B., Lupher, Mark L., Ota, Satoshi, Bowtell, David D. L., Scaife, Robin M., Langdon, Wallace Y., Band, Hamid
Publicado 2000

The Ubiquitin Ligase Component Siah1a Is Required for Completion of Meiosis I in Male Mice

por Dickins, Ross A., Frew, Ian J., House, Colin M., O'Bryan, Moira K., Holloway, Andrew J., Haviv, Izhak, Traficante, Nadia, de Kretser, David M., Bowtell, David D. L.
Publicado 2002

Synthetic lethality between CCNE1 amplification and loss of BRCA1

por Etemadmoghadam, Dariush, Weir, Barbara A., Au-Yeung, George, Alsop, Kathryn, Mitchell, Gillian, George, Joshy, Davis, Sally, D’Andrea, Alan D., Simpson, Kaylene, Hahn, William C., Bowtell, David D. L.
Publicado 2013

Transducin-Like Enhancer of Split 3 (TLE3) expression is associated with taxane sensitivity in non-serous ovarian carcinoma in a three-cohort study

por Ring, Brian Z., Murali, Rajmohan, Soslow, Robert A., Bowtell, David D.L., Fereday, Sian, deFazio, Anna, Traficante, Nadia, Kennedy, Catherine J, Brand, Alison, Sharma, Raghwa, Harnett, Paul, Samimi, Goli
Publicado en Cancer Epidemiol Biomarkers Prev (2018)

Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

por Ryland, Georgina L., Hunter, Sally M., Doyle, Maria A., Caramia, Franco, Li, Jason, Rowley, Simone M., Christie, Michael, Allan, Prue E., Stephens, Andrew N., Bowtell, David D L, Campbell, Ian G., Gorringe, Kylie L.
Publicado en Genome Med (2015)

Erratum to: Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors

por Ryland, Georgina L., Hunter, Sally M., Doyle, Maria A., Caramia, Franco, Li, Jason, Rowley, Simone M., Christie, Michael, Allan, Prue E., Stephens, Andrew N., Bowtell, David D. L., Campbell, Ian G., Gorringe, Kylie L.
Publicado en Genome Med (2017)

c-Cbl–deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action

por Molero, Juan C., Jensen, Thomas E., Withers, Phil C., Couzens, Michelle, Herzog, Herbert, Thien, Christine B.F., Langdon, Wallace Y., Walder, Ken, Murphy, Maria A., Bowtell, David D.L., James, David E., Cooney, Gregory J.
Publicado 2004