Protease Cleavage Sites in HIV-1 gp120 Recognized by Antigen Processing Enzymes Are Conserved and Located at Receptor Binding Sites

by Yu, Bin, Fonseca, Dora P. A. J., O'Rourke, Sara M., Berman, Phillip W.
Published 2010

Glycoform and Net Charge Heterogeneity in gp120 Immunogens Used in HIV Vaccine Trials

by Yu, Bin, Morales, Javier F., O'Rourke, Sara M., Tatsuno, Gwen P., Berman, Phillip W.
Published 2012

Phylodynamics of HIV-1 from a Phase-III AIDS Vaccine Trial in North America

by Pérez-Losada, Marcos, Jobes, David V., Sinangil, Faruk, Crandall, Keith A., Posada, David, Berman, Phillip W.
Published 2010

Identification and CRISPR/Cas9 Knockout of the Endogenous C1s Protease in CHO Cells Eliminates Aberrant Proteolysis of Recombinantly Expressed Proteins

by Li, Sophia, Yu, Bin, Byrne, Gabriel, Wright, Meredith, O’Rourke, Sara, Mesa, Kathryn, Berman, Phillip W.
Published in Biotechnol Bioeng (2019)

Fragments of the V1/V2 Domain of HIV-1 Glycoprotein 120 Engineered for Improved Binding to the Broadly Neutralizing PG9 Antibody

by Morales, Javier F., Yu, Bin, Perez, Gerardo, Mesa, Kathryn A., Alexander, David L., Berman, Phillip W.
Published in Mol Immunol (2016)

Ethnic differences in the adaptation rate of HIV gp120 from a vaccine trial

by Pérez-Losada, Marcos, Posada, David, Arenas, Miguel, Jobes, David V, Sinangil, Faruk, Berman, Phillip W, Crandall, Keith A
Published 2009

Phylodynamics of HIV-1 from a Phase III AIDS Vaccine Trial in Bangkok, Thailand

by Pérez-Losada, Marcos, Jobes, David V., Sinangil, Faruk, Crandall, Keith A., Arenas, Miguel, Posada, David, Berman, Phillip W.
Published 2011

Monoclonal Antibodies to the V2 Domain of MN-rgp120: Fine Mapping of Epitopes and Inhibition of α4β7 Binding

by Nakamura, Gerald R., Fonseca, Dora P. A. J., O'Rourke, Sara M., Vollrath, Aaron L., Berman, Phillip W.
Published 2012

Production of a recombinant monoclonal antibody to Herpes Simplex Virus glycoprotein D for immunoaffinity purification of tagged proteins

by O’Rourke, Sara M., Yu, Bin, Morales, Javier F., Didinger, Chelsea M., Alexander, David L., Vollmers, Christopher, Berman, Phillip W.
Published in J Immunol Methods (2018)

Novel Ring Structure in the gp41 Trimer of Human Immunodeficiency Virus Type 1 That Modulates Sensitivity and Resistance to Broadly Neutralizing Antibodies

by O'Rourke, Sara M., Schweighardt, Becky, Scott, William G., Wrin, Terri, Fonseca, Dora P. A. J., Sinangil, Faruk, Berman, Phillip W.
Published 2009

Comparative Immunogenicity of HIV-1 Clade C Envelope Proteins for Prime/Boost Studies

by Smith, Douglas H., Winters-Digiacinto, Peggy, Mitiku, Misrach, O'Rourke, Sara, Sinangil, Faruk, Wrin, Terri, Montefiori, David C., Berman, Phillip W.
Published 2010

Glycan modifications to the gp120 immunogens used in the RV144 vaccine trial improve binding to broadly neutralizing antibodies

by Doran, Rachel C., Tatsuno, Gwen P., O’Rourke, Sara M., Yu, Bin, Alexander, David L., Mesa, Kathryn A., Berman, Phillip W.
Published in PLoS One (2018)

Mutation at a Single Position in the V2 Domain of the HIV-1 Envelope Protein Confers Neutralization Sensitivity to a Highly Neutralization-Resistant Virus

by O'Rourke, Sara M., Schweighardt, Becky, Phung, Pham, Fonseca, Dora P. A. J., Terry, Karianne, Wrin, Terri, Sinangil, Faruk, Berman, Phillip W.
Published 2010

Peptide Targeted by Human Antibodies Associated with HIV Vaccine-Associated Protection Assumes a Dynamic α-Helical Structure

by Aiyegbo, Mohammed S., Shmelkov, Evgeny, Dominguez, Lorenzo, Goger, Michael, Battacharya, Shibani, deCamp, Allan C., Gilbert, Peter B., Berman, Phillip W., Cardozo, Timothy
Published in PLoS One (2017)

Gene editing in CHO cells to prevent proteolysis and enhance glycosylation: Production of HIV envelope proteins as vaccine immunogens

by Li, Sophia W., Wright, Meredith, Healey, John F., Hutchinson, Jennie M., O’Rourke, Sara, Mesa, Kathryn A., Lollar, Pete, Berman, Phillip W.
Published in PLoS One (2020)

HIV-1 Envelope Proteins and V1/V2 Domain Scaffolds with Mannose-5 to Improve the Magnitude and Quality of Protective Antibody Responses to HIV-1

by Morales, Javier F., Morin, Trevor J., Yu, Bin, Tatsuno, Gwen P., O'Rourke, Sara M., Theolis, Richard, Mesa, Kathryn A., Berman, Phillip W.
Published 2014

Robotic selection for the rapid development of stable CHO cell lines for HIV vaccine production

by O’Rourke, Sara M., Byrne, Gabriel, Tatsuno, Gwen, Wright, Meredith, Yu, Bin, Mesa, Kathryn A., Doran, Rachel C., Alexander, David, Berman, Phillip W.
Published in PLoS One (2018)

CRISPR/Cas9 gene editing for the creation of an MGAT1-deficient CHO cell line to control HIV-1 vaccine glycosylation

by Byrne, Gabriel, O’Rourke, Sara M., Alexander, David L., Yu, Bin, Doran, Rachel C., Wright, Meredith, Chen, Qiushi, Azadi, Parastoo, Berman, Phillip W.
Published in PLoS Biol (2018)

Glycans Flanking the Hypervariable Connecting Peptide between the A and B Strands of the V1/V2 Domain of HIV-1 gp120 Confer Resistance to Antibodies That Neutralize CRF01_AE Viruse...

by O’Rourke, Sara M., Sutthent, Ruengpung, Phung, Pham, Mesa, Kathryn A., Frigon, Normand L., To, Briana, Horthongkham, Navin, Limoli, Kay, Wrin, Terri, Berman, Phillip W.
Published in PLoS One (2015)

Development of a Stable MGAT1(−) CHO Cell Line to Produce Clade C gp120 With Improved Binding to Broadly Neutralizing Antibodies

by Doran, Rachel C., Yu, Bin, Wright, Meredith, O'Rourke, Sara M., Yin, Lu, Richardson, Jennie M., Byrne, Gabriel, Mesa, Kathryn A., Berman, Phillip W.
Published in Front Immunol (2018)