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HIV-1 Envelope Proteins and V1/V2 Domain Scaffolds with Mannose-5 to Improve the Magnitude and Quality of Protective Antibody Responses to HIV-1

Two lines of investigation have highlighted the importance of antibodies to the V1/V2 domain of gp120 in providing protection from HIV-1 infection. First, the recent RV144 HIV-1 vaccine trial documented a correlation between non-neutralizing antibodies to the V2 domain and protection. Second, multip...

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書誌詳細
主要な著者: Morales, Javier F., Morin, Trevor J., Yu, Bin, Tatsuno, Gwen P., O'Rourke, Sara M., Theolis, Richard, Mesa, Kathryn A., Berman, Phillip W.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110267/
https://ncbi.nlm.nih.gov/pubmed/24872420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554089
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