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Protease Cleavage Sites in HIV-1 gp120 Recognized by Antigen Processing Enzymes Are Conserved and Located at Receptor Binding Sites

The identification of vaccine immunogens able to elicit broadly neutralizing antibodies (bNAbs) is a major goal in HIV vaccine research. Although it has been possible to produce recombinant envelope glycoproteins able to adsorb bNAbs from HIV-positive sera, immunization with these proteins has faile...

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Bibliografiske detaljer
Main Authors: Yu, Bin, Fonseca, Dora P. A. J., O'Rourke, Sara M., Berman, Phillip W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812349/
https://ncbi.nlm.nih.gov/pubmed/19939935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01765-09
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