Development of a Stable MGAT1(−) CHO Cell Line to Produce Clade C gp120 With Improved Binding to Broadly Neutralizing Antibodies

The high rate of new HIV infections, particularly in Sub-Saharan Africa, emphasizes the need for a safe and effective vaccine to prevent acquired immunodeficiency syndrome (AIDS). To date, the only HIV vaccine trial that has exhibited protective efficacy in humans was the RV144 study completed in Th...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Doran, Rachel C., Yu, Bin, Wright, Meredith, O'Rourke, Sara M., Yin, Lu, Richardson, Jennie M., Byrne, Gabriel, Mesa, Kathryn A., Berman, Phillip W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6182045/
https://ncbi.nlm.nih.gov/pubmed/30344523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02313
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