Glycans Flanking the Hypervariable Connecting Peptide between the A and B Strands of the V1/V2 Domain of HIV-1 gp120 Confer Resistance to Antibodies That Neutralize CRF01_AE Viruses

Understanding the molecular determinants of sensitivity and resistance to neutralizing antibodies is critical for the development of vaccines designed to prevent HIV infection. In this study, we used a genetic approach to characterize naturally occurring polymorphisms in the HIV envelope protein tha...

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Bibliographic Details
Published in:PLoS One
Main Authors: O’Rourke, Sara M., Sutthent, Ruengpung, Phung, Pham, Mesa, Kathryn A., Frigon, Normand L., To, Briana, Horthongkham, Navin, Limoli, Kay, Wrin, Terri, Berman, Phillip W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368187/
https://ncbi.nlm.nih.gov/pubmed/25793890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119608
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