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Mutation at a Single Position in the V2 Domain of the HIV-1 Envelope Protein Confers Neutralization Sensitivity to a Highly Neutralization-Resistant Virus

Understanding the determinants of neutralization sensitivity and resistance is important for the development of an effective human immunodeficiency virus type 1 (HIV-1) vaccine. In these studies, we have made use of the swarm of closely related envelope protein variants (quasispecies) from an extrem...

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Detalhes bibliográficos
Main Authors: O'Rourke, Sara M., Schweighardt, Becky, Phung, Pham, Fonseca, Dora P. A. J., Terry, Karianne, Wrin, Terri, Sinangil, Faruk, Berman, Phillip W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953176/
https://ncbi.nlm.nih.gov/pubmed/20702624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00790-10
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