Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

Por Baud, Véronique, Liu, Zheng-Gang, Bennett, Brydon, Suzuki, Nobutaka, Xia, Ying, Karin, Michael
Publicado em 1999

Allergen-induced inflammation and airway epithelial and smooth muscle cell proliferation: role of Jun N-terminal kinase

Por Eynott, Paul R, Nath, Puneeta, Leung, Sum-Yee, Adcock, Ian M, Bennett, Brydon L, Chung, K Fan
Publicado em 2003

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

Por Han, Zuoning, Boyle, David L., Chang, Lufen, Bennett, Brydon, Karin, Michael, Yang, Li, Manning, Anthony M., Firestein, Gary S.
Publicado em 2001

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

Por Han, Zuoning, Boyle, David L., Chang, Lufen, Bennett, Brydon, Karin, Michael, Yang, Li, Manning, Anthony M., Firestein, Gary S.
Publicado em 2001

Effect of an inhibitor of Jun N-terminal protein kinase, SP600125, in single allergen challenge in sensitized rats

Por Eynott, Paul R, Xu, Li, Bennett, Brydon L, Noble, Alistair, Leung, Sum-Yee, Nath, Puneeta, Groneberg, David A, Adcock, Ian M, Chung, K Fan
Publicado em 2004

IκB Kinase (IKK)-Associated Protein 1, a Common Component of the Heterogeneous IKK Complex

Por Mercurio, Frank, Murray, Brion W., Shevchenko, Andrej, Bennett, Brydon L., Young, David B., Li, Jian Wu, Pascual, Gabriel, Motiwala, Aparna, Zhu, Hengyi, Mann, Matthias, Manning, Anthony M.
Publicado em 1999

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

Por Bennett, Brydon L., Sasaki, Dennis T., Murray, Brion W., O'Leary, Eoin C., Sakata, Steve T., Xu, Weiming, Leisten, Jim C., Motiwala, Aparna, Pierce, Steve, Satoh, Yoshitaka, Bhagwat, Shripad S., Manning, Anthony M., Anderson, David W.
Publicado em 2001

JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers

Por van der Velden, Jos L. J., Ye, Ying, Nolin, James D., Hoffman, Sidra M., Chapman, David G., Lahue, Karolyn G., Abdalla, Sarah, Chen, Peng, Liu, Yong, Bennett, Brydon, Khalil, Nasreen, Sutherland, Donna, Smith, William, Horan, Gerald, Assaf, Mahmoud, Horowitz, Zebulun, Chopra, Rajesh, Stevens, Randall M., Palmisano, Maria, Janssen-Heininger, Yvonne M. W., Schafer, Peter H.
Publicado no Clin Transl Med (2016)

A Novel Triazolopyridine-Based Spleen Tyrosine Kinase Inhibitor That Arrests Joint Inflammation

Por Ferguson, Gregory D., Delgado, Mercedes, Plantevin-Krenitsky, Veronique, Jensen-Pergakes, Kristen, Bates, R. J., Torres, Sanaa, Celeridad, Maria, Brown, Heather, Burnett, Kelven, Nadolny, Lisa, Tehrani, Lida, Packard, Garrick, Pagarigan, Barbra, Haelewyn, Jason, Nguyen, Trish, Xu, Li, Tang, Yang, Hickman, Matthew, Baculi, Frans, Pierce, Steven, Miyazawa, Keiji, Jackson, Pilgrim, Chamberlain, Philip, LeBrun, Laurie, Xie, Weilin, Bennett, Brydon, Blease, Kate
Publicado no PLoS One (2016)