Effect of an inhibitor of Jun N-terminal protein kinase, SP600125, in single allergen challenge in sensitized rats

Jun N-terminal kinase (JNK) has been implicated in the pathogenesis of inflammatory diseases including asthma. We examined the effect of SP600125 (anthra [1,9-cd] pyrazol-6 (2H)-one), a novel inhibitor of JNK in a model of asthma. Brown-Norway rats were sensitized to ovalbumin and treated with SP600...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Eynott, Paul R, Xu, Li, Bennett, Brydon L, Noble, Alistair, Leung, Sum-Yee, Nath, Puneeta, Groneberg, David A, Adcock, Ian M, Chung, K Fan
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Science Inc 2004
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782503/
https://ncbi.nlm.nih.gov/pubmed/15196213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01887.x
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