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Inhibition of adrenergic human prostate smooth muscle contraction by the inhibitors of c-Jun N-terminal kinase, SP600125 and BI-78D3

BACKGROUND AND PURPOSE: α(1)-Adrenoceptor-induced contraction of prostate smooth muscle is mediated by calcium- and Rho kinase-dependent mechanisms. In addition, other mechanisms, such as activation of c-jun N-terminal kinase (JNK) may be involved. Here, we investigated whether JNK participates in α...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Strittmatter, F, Walther, S, Gratzke, C, Göttinger, J, Beckmann, C, Roosen, A, Schlenker, B, Hedlund, P, Andersson, KE, Stief, CG, Hennenberg, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402815/
https://ncbi.nlm.nih.gov/pubmed/22364229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01919.x
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