RNA-mediated toxicity in neurodegenerative disease

Por Belzil, Veronique V., Gendron, Tania F., Petrucelli, Leonard
Publicado em 2012

ALS and FTD: an epigenetic perspective

Por Belzil, Veronique V., Katzman, Rebecca B., Petrucelli, Leonard
Publicado no Acta Neuropathol (2016)

Mechanisms of Toxicity in C9FTLD/ALS

Por Gendron, Tania F., Belzil, Veronique V., Zhang, Yong-Jie, Petrucelli, Leonard
Publicado em 2014

Genetic analysis of SIGMAR1 as a cause of familial ALS with dementia

Por Belzil, Véronique V, Daoud, Hussein, Camu, William, Strong, Michael J, Dion, Patrick A, Rouleau, Guy A
Publicado em 2013

Characterization of DNA hypermethylation in the cerebellum of c9FTD/ALS patients

Por Belzil, Veronique V., Bauer, Peter O., Gendron, Tania F., Murray, Melissa E., Dickson, Dennis, Petrucelli, Leonard
Publicado em 2014

Sensory and motor neuronopathy in a patient with the A382P TDP-43 mutation

Por Camdessanché, Jean-Philippe, Belzil, Véronique V, Jousserand, Guillemette, Rouleau, Guy A, Créac'h, Christelle, Convers, Philippe, Antoine, Jean-Christophe
Publicado em 2011

C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells

Por Esanov, Rustam, Belle, Kinsley C., van Blitterswijk, Marka, Belzil, Veronique V., Rademakers, Rosa, Dickson, Dennis W., Petrucelli, Leonard, Boylan, Kevin B., Dykxhoorn, Derek M., Wuu, Joanne, Benatar, Michael, Wahlestedt, Claes, Zeier, Zane
Publicado no Exp Neurol (2015)

Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood

Por Belzil, Veronique V., Bauer, Peter O., Prudencio, Mercedes, Gendron, Tania F., Stetler, Caroline T., Yan, Irene K., Pregent, Luc, Daughrity, Lillian, Baker, Matthew C., Rademakers, Rosa, Boylan, Kevin, Patel, Tushar C., Dickson, Dennis W., Petrucelli, Leonard
Publicado em 2013

Deleterious mutations in the essential mRNA metabolism factor, hGle1, in amyotrophic lateral sclerosis

Por Kaneb, Hannah M., Folkmann, Andrew W., Belzil, Véronique V., Jao, Li-En, Leblond, Claire S., Girard, Simon L., Daoud, Hussein, Noreau, Anne, Rochefort, Daniel, Hince, Pascale, Szuto, Anna, Levert, Annie, Vidal, Sabrina, André-Guimont, Catherine, Camu, William, Bouchard, Jean-Pierre, Dupré, Nicolas, Rouleau, Guy A., Wente, Susan R., Dion, Patrick A.
Publicado no Hum Mol Genet (2015)

Conserved DNA methylation combined with differential frontal cortex and cerebellar expression distinguishes C9orf72-associated and sporadic ALS, and implicates SERPINA1 in disease

Por Ebbert, Mark T. W., Ross, Christian A., Pregent, Luc J., Lank, Rebecca J., Zhang, Cheng, Katzman, Rebecca B., Jansen-West, Karen, Song, Yuping, da Rocha, Edroaldo Lummertz, Palmucci, Carla, Desaro, Pamela, Robertson, Amelia E., Caputo, Ana M., Dickson, Dennis W., Boylan, Kevin B., Rademakers, Rosa, Ordog, Tamas, 4-5, Li, Hu, Belzil, Veronique V.
Publicado no Acta Neuropathol (2017)

Exome Sequencing Identifies FUS Mutations as a Cause of Essential Tremor

Por Merner, Nancy D., Girard, Simon L., Catoire, Hélène, Bourassa, Cynthia V., Belzil, Véronique V., Rivière, Jean-Baptiste, Hince, Pascale, Levert, Annie, Dionne-Laporte, Alexandre, Spiegelman, Dan, Noreau, Anne, Diab, Sabrina, Szuto, Anna, Fournier, Hélène, Raelson, John, Belouchi, Majid, Panisset, Michel, Cossette, Patrick, Dupré, Nicolas, Bernard, Geneviève, Chouinard, Sylvain, Dion, Patrick A., Rouleau, Guy A.
Publicado em 2012

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

Por Zhang, Yong-Jie, Jansen-West, Karen, Xu, Ya-Fei, Gendron, Tania F., Bieniek, Kevin F., Lin, Wen-Lang, Sasaguri, Hiroki, Caulfield, Thomas, Hubbard, Jaime, Daughrity, Lillian, Chew, Jeannie, Belzil, Veronique V., Prudencio, Mercedes, Stankowski, Jeannette N., Castanedes-Casey, Monica, Whitelaw, Ena, Ash, Peter E. A., DeTure, Michael, Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard
Publicado em 2014

Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS

Por Prudencio, Mercedes, Belzil, Veronique V., Batra, Ranjan, Ross, Christian A., Gendron, Tania F., Pregent, Luc J., Murray, Melissa E., Overstreet, Karen K., Piazza-Johnston, Amelia E., Desaro, Pamela, Bieniek, Kevin F., DeTure, Michael, Lee, Wing C., Biendarra, Sherri M., Davis, Mary D., Baker, Matthew C., Perkerson, Ralph B., van Blitterswijk, Marka, Stetler, Caroline T., Rademakers, Rosa, Link, Christopher D., Dickson, Dennis W., Boylan, Kevin B., Li, Hu, Petrucelli, Leonard
Publicado no Nat Neurosci (2015)

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

Por Su, Zhaoming, Zhang, Yongjie, Gendron, Tania F., Bauer, Peter O., Chew, Jeannie, Yang, Wang-Yong, Fostvedt, Erik, Jansen-West, Karen, Belzil, Veronique V., Desaro, Pamela, Johnston, Amelia, Overstreet, Karen, Oh, Seok-Yoon, Todd, Peter K., Berry, James D., Cudkowicz, Merit E., Boeve, Bradley F., Dickson, Dennis, Floeter, Mary Kay, Traynor, Bryan J., Morelli, Claudia, Ratti, Antonia, Silani, Vincenzo, Rademakers, Rosa, Brown, Robert H., Rothstein, Jeffrey D., Boylan, Kevin B., Petrucelli, Leonard, Disney, Matthew D.
Publicado no Neuron (2014)

ERBB4 Mutations that Disrupt the Neuregulin-ErbB4 Pathway Cause Amyotrophic Lateral Sclerosis Type 19

Por Takahashi, Yuji, Fukuda, Yoko, Yoshimura, Jun, Toyoda, Atsushi, Kurppa, Kari, Moritoyo, Hiroyoko, Belzil, Veronique V., Dion, Patrick A., Higasa, Koichiro, Doi, Koichiro, Ishiura, Hiroyuki, Mitsui, Jun, Date, Hidetoshi, Ahsan, Budrul, Matsukawa, Takashi, Ichikawa, Yaeko, Moritoyo, Takashi, Ikoma, Mayumi, Hashimoto, Tsukasa, Kimura, Fumiharu, Murayama, Shigeo, Onodera, Osamu, Nishizawa, Masatoyo, Yoshida, Mari, Atsuta, Naoki, Sobue, Gen, Fifita, Jennifer A., Williams, Kelly L., Blair, Ian P., Nicholson, Garth A., Gonzalez-Perez, Paloma, Brown, Robert H., Nomoto, Masahiro, Elenius, Klaus, Rouleau, Guy A., Fujiyama, Asao, Morishita, Shinichi, Goto, Jun, Tsuji, Shoji
Publicado em 2013