Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood

Individuals carrying (GGGGCC) expanded repeats in the C9orf72 gene represent a significant portion of patients suffering from amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Elucidating how these expanded repeats cause “c9FTD/ALS” has since become an important goal of the fiel...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Belzil, Veronique V., Bauer, Peter O., Prudencio, Mercedes, Gendron, Tania F., Stetler, Caroline T., Yan, Irene K., Pregent, Luc, Daughrity, Lillian, Baker, Matthew C., Rademakers, Rosa, Boylan, Kevin, Patel, Tushar C., Dickson, Dennis W., Petrucelli, Leonard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2013
Onderwerpen:
Original Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3830740/
https://ncbi.nlm.nih.gov/pubmed/24166615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1199-1
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items