RNA-mediated toxicity in neurodegenerative disease

par Belzil, Veronique V., Gendron, Tania F., Petrucelli, Leonard
Publié 2012

ALS and FTD: an epigenetic perspective

par Belzil, Veronique V., Katzman, Rebecca B., Petrucelli, Leonard
Publié dans Acta Neuropathol (2016)

Mechanisms of Toxicity in C9FTLD/ALS

par Gendron, Tania F., Belzil, Veronique V., Zhang, Yong-Jie, Petrucelli, Leonard
Publié 2014

Genetic analysis of SIGMAR1 as a cause of familial ALS with dementia

par Belzil, Véronique V, Daoud, Hussein, Camu, William, Strong, Michael J, Dion, Patrick A, Rouleau, Guy A
Publié 2013

Characterization of DNA hypermethylation in the cerebellum of c9FTD/ALS patients

par Belzil, Veronique V., Bauer, Peter O., Gendron, Tania F., Murray, Melissa E., Dickson, Dennis, Petrucelli, Leonard
Publié 2014

Sensory and motor neuronopathy in a patient with the A382P TDP-43 mutation

par Camdessanché, Jean-Philippe, Belzil, Véronique V, Jousserand, Guillemette, Rouleau, Guy A, Créac'h, Christelle, Convers, Philippe, Antoine, Jean-Christophe
Publié 2011

C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells

par Esanov, Rustam, Belle, Kinsley C., van Blitterswijk, Marka, Belzil, Veronique V., Rademakers, Rosa, Dickson, Dennis W., Petrucelli, Leonard, Boylan, Kevin B., Dykxhoorn, Derek M., Wuu, Joanne, Benatar, Michael, Wahlestedt, Claes, Zeier, Zane
Publié dans Exp Neurol (2015)

Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood

par Belzil, Veronique V., Bauer, Peter O., Prudencio, Mercedes, Gendron, Tania F., Stetler, Caroline T., Yan, Irene K., Pregent, Luc, Daughrity, Lillian, Baker, Matthew C., Rademakers, Rosa, Boylan, Kevin, Patel, Tushar C., Dickson, Dennis W., Petrucelli, Leonard
Publié 2013

ADAR2 Mislocalization and Widespread RNA Editing Aberrations in C9orf72-Mediated ALS/FTD

par Moore, Stephen, Alsop, Eric, Lorenzini, Ileana, Starr, Alexander, Rabichow, Benjamin E., Mendez, Emily, Levy, Jennifer L., Burciu, Camelia, Reiman, Rebecca, Chew, Jeannie, Belzil, Veronique V., Dickson, Dennis, Robertson, Janice, Staats, Kim A., Ichida, Justin K., Petrucelli, Leonard, Keuren-Jensen, Kendall Van, Sattler, Rita
Publié dans Acta Neuropathol (2019)

Deleterious mutations in the essential mRNA metabolism factor, hGle1, in amyotrophic lateral sclerosis

par Kaneb, Hannah M., Folkmann, Andrew W., Belzil, Véronique V., Jao, Li-En, Leblond, Claire S., Girard, Simon L., Daoud, Hussein, Noreau, Anne, Rochefort, Daniel, Hince, Pascale, Szuto, Anna, Levert, Annie, Vidal, Sabrina, André-Guimont, Catherine, Camu, William, Bouchard, Jean-Pierre, Dupré, Nicolas, Rouleau, Guy A., Wente, Susan R., Dion, Patrick A.
Publié dans Hum Mol Genet (2015)

Conserved DNA methylation combined with differential frontal cortex and cerebellar expression distinguishes C9orf72-associated and sporadic ALS, and implicates SERPINA1 in disease

par Ebbert, Mark T. W., Ross, Christian A., Pregent, Luc J., Lank, Rebecca J., Zhang, Cheng, Katzman, Rebecca B., Jansen-West, Karen, Song, Yuping, da Rocha, Edroaldo Lummertz, Palmucci, Carla, Desaro, Pamela, Robertson, Amelia E., Caputo, Ana M., Dickson, Dennis W., Boylan, Kevin B., Rademakers, Rosa, Ordog, Tamas, 4-5, Li, Hu, Belzil, Veronique V.
Publié dans Acta Neuropathol (2017)

Exome Sequencing Identifies FUS Mutations as a Cause of Essential Tremor

par Merner, Nancy D., Girard, Simon L., Catoire, Hélène, Bourassa, Cynthia V., Belzil, Véronique V., Rivière, Jean-Baptiste, Hince, Pascale, Levert, Annie, Dionne-Laporte, Alexandre, Spiegelman, Dan, Noreau, Anne, Diab, Sabrina, Szuto, Anna, Fournier, Hélène, Raelson, John, Belouchi, Majid, Panisset, Michel, Cossette, Patrick, Dupré, Nicolas, Bernard, Geneviève, Chouinard, Sylvain, Dion, Patrick A., Rouleau, Guy A.
Publié 2012

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

par Zhang, Yong-Jie, Jansen-West, Karen, Xu, Ya-Fei, Gendron, Tania F., Bieniek, Kevin F., Lin, Wen-Lang, Sasaguri, Hiroki, Caulfield, Thomas, Hubbard, Jaime, Daughrity, Lillian, Chew, Jeannie, Belzil, Veronique V., Prudencio, Mercedes, Stankowski, Jeannette N., Castanedes-Casey, Monica, Whitelaw, Ena, Ash, Peter E. A., DeTure, Michael, Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard
Publié 2014

Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS

par Prudencio, Mercedes, Belzil, Veronique V., Batra, Ranjan, Ross, Christian A., Gendron, Tania F., Pregent, Luc J., Murray, Melissa E., Overstreet, Karen K., Piazza-Johnston, Amelia E., Desaro, Pamela, Bieniek, Kevin F., DeTure, Michael, Lee, Wing C., Biendarra, Sherri M., Davis, Mary D., Baker, Matthew C., Perkerson, Ralph B., van Blitterswijk, Marka, Stetler, Caroline T., Rademakers, Rosa, Link, Christopher D., Dickson, Dennis W., Boylan, Kevin B., Li, Hu, Petrucelli, Leonard
Publié dans Nat Neurosci (2015)

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

par Su, Zhaoming, Zhang, Yongjie, Gendron, Tania F., Bauer, Peter O., Chew, Jeannie, Yang, Wang-Yong, Fostvedt, Erik, Jansen-West, Karen, Belzil, Veronique V., Desaro, Pamela, Johnston, Amelia, Overstreet, Karen, Oh, Seok-Yoon, Todd, Peter K., Berry, James D., Cudkowicz, Merit E., Boeve, Bradley F., Dickson, Dennis, Floeter, Mary Kay, Traynor, Bryan J., Morelli, Claudia, Ratti, Antonia, Silani, Vincenzo, Rademakers, Rosa, Brown, Robert H., Rothstein, Jeffrey D., Boylan, Kevin B., Petrucelli, Leonard, Disney, Matthew D.
Publié dans Neuron (2014)

ERBB4 Mutations that Disrupt the Neuregulin-ErbB4 Pathway Cause Amyotrophic Lateral Sclerosis Type 19

par Takahashi, Yuji, Fukuda, Yoko, Yoshimura, Jun, Toyoda, Atsushi, Kurppa, Kari, Moritoyo, Hiroyoko, Belzil, Veronique V., Dion, Patrick A., Higasa, Koichiro, Doi, Koichiro, Ishiura, Hiroyuki, Mitsui, Jun, Date, Hidetoshi, Ahsan, Budrul, Matsukawa, Takashi, Ichikawa, Yaeko, Moritoyo, Takashi, Ikoma, Mayumi, Hashimoto, Tsukasa, Kimura, Fumiharu, Murayama, Shigeo, Onodera, Osamu, Nishizawa, Masatoyo, Yoshida, Mari, Atsuta, Naoki, Sobue, Gen, Fifita, Jennifer A., Williams, Kelly L., Blair, Ian P., Nicholson, Garth A., Gonzalez-Perez, Paloma, Brown, Robert H., Nomoto, Masahiro, Elenius, Klaus, Rouleau, Guy A., Fujiyama, Asao, Morishita, Shinichi, Goto, Jun, Tsuji, Shoji
Publié 2013